The Las Vegas Valley metropolitan area is the largest within the greater Mojave Desert, and 2nd-largest in the Southwestern United States. Las Vegas ( US: / l ɑː s ˈ v eɪ ɡ ə s/ lahss VAY-gəss from Spanish las vegas 'the meadows'), often known simply as Vegas, is the 25th-most populous city in the United States, the most populous city in the state of Nevada, and the county seat of Clark County.